Neurodegeneration and regeneration
نویسندگان
چکیده
منابع مشابه
Mechanisms of neurodegeneration and regeneration in alcoholism.
AIMS This is a review of preclinical studies covering alcohol-induced brain neuronal death and loss of neurogenesis as well as abstinence-induced brain cell genesis, e.g. brain regeneration. Efforts are made to relate preclinical studies to human studies. METHODS The studies described are preclinical rat experiments using a 4-day binge ethanol treatment known to induce physical dependence to ...
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During the past three decades, Wingless/Int (Wnt) signaling has emerged as an essential regulator crucial for neuronal development and maintenance (Inestrosa and Arenas, 2010). In addition, Wnt signaling was recently shown to be involved in the regulation of synaptic function and plasticity, which is critical for learning and memory (Oliva et al., 2013). Deregulation of Wnt signaling has been p...
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Enolase is a multifunctional enzyme primarily involved in catalyzing the conversion of 2phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis[1–4]. Though typically expressed in the cytosol, enolase has been shown to migrate to the cell surface upon inflammatory signal[3]. It then enhances antigen presentation for the invasion of host cells vi...
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Iron is a trace element of considerable interest to both chemistry and biology. In a biological context its chemistry is vital to the roles it performs. However, that same chemistry can contribute to a more deleterious role in a variety of diseases. The brain is a very sensitive organ due to the irreplaceable nature of neurons. In this regard regulation of brain iron chemistry is essential to m...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Research
سال: 2017
ISSN: 0360-4012
DOI: 10.1002/jnr.24069